HUAIER RELIEVES OXALIPLATIN-INDUCED HEPATOTOXICITY THROUGH ACTIVATION OF THE PI3K/AKT/NRF2 SIGNALING PATHWAY IN C57BL/6 MICE

Huaier relieves oxaliplatin-induced hepatotoxicity through activation of the PI3K/AKT/Nrf2 signaling pathway in C57BL/6 mice

Hepatotoxicity caused by the anticancer medication oxaliplatin (OXA) Power Plug Adaptors significantly restricts its clinical use and raises the risk of liver damage.Huaier, a fungus found in China, has been demonstrated to have various beneficial effects in adjuvant therapy for cancer.However, the preventive impact of Huaier against OXA-induced he

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Challenges and opportunities in the immunotherapy era: balancing expectations with hope in small-cell lung cancer

Small-cell lung cancer (SCLC) is a biologically aggressive subtype of lung cancer, a lethal disease characterized by rapid tumor growth, early relapse, a strong tendency for early widespread metastasis, and high genomic instability, making it a formidable foe in modern oncology practice.While the management of non-SCLC has been revolutionized in th

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